Effects of oxygen transport on 3-d human mesenchymal stem cell metabolic activity in perfusion and static cultures: experiments and mathematical model.

@article{Zhao2005EffectsOO,
  title={Effects of oxygen transport on 3-d human mesenchymal stem cell metabolic activity in perfusion and static cultures: experiments and mathematical model.},
  author={Feng Zhao and Pragyansri Pathi and Warren L Grayson and Qi Chong Xing and Bruce R. Locke and Teng Ma},
  journal={Biotechnology progress},
  year={2005},
  volume={21 4},
  pages={1269-80}
}
Human mesenchymal stem cells (hMSCs) have unique potential to develop into functional tissue constructs to replace a wide range of tissues damaged by disease or injury. While recent studies have highlighted the necessity for 3-D culture systems to facilitate the proper biological, physiological, and developmental processes of the cells, the effects of the physiological environment on the intrinsic tissue development characteristics in the 3-D scaffolds have not been fully investigated. In this… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Directing the spatial patterning of motor neuron differentiation in engineered microenvironments

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) • 2016

Similar Papers

Loading similar papers…