Effects of oxygen tension on gene expression in preimplantation mouse embryos.

@article{Rinaudo2006EffectsOO,
  title={Effects of oxygen tension on gene expression in preimplantation mouse embryos.},
  author={Paolo F. Rinaudo and Gnanaratnam Giritharan and Said Talbi and Anthony Dobson and Richard M Schultz},
  journal={Fertility and sterility},
  year={2006},
  volume={86 4 Suppl},
  pages={1252-65, 1265.e1-36}
}
OBJECTIVE To compare the effects of atmospheric and physiologic oxygen concentrations on the global patterns of gene expression during mouse preimplantation development. DESIGN Comparative analysis of in vivo-produced and in vitro-produced embryos. SETTING Research laboratory. PATIENT(S) None. INTERVENTION(S) Control embryos at the blastocyst stage that developed in vivo were collected from uteri. Experimental embryos were obtained at the zygote stage and cultured to the blastocyst… CONTINUE READING
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