Effects of oxygen tension and pH on the respiratory burst of human neutrophils.

@article{Gabig1979EffectsOO,
  title={Effects of oxygen tension and pH on the respiratory burst of human neutrophils.},
  author={Theodore G. Gabig and Scott I. Bearman and Bernard M. Babior},
  journal={Blood},
  year={1979},
  volume={53 6},
  pages={1133-9}
}
The respiratory burst of human neutrophils was measured under conditions of hypoxia and low pH. O2 -- production by neutrophils activated with opsonized zymosan fell slowly as the oxygen concentration declined to 1%, then dropped more sharply, reaching negligible levels at oxygen concentrations less than 0.25%. Production was half maximal at an oxygen concentration of 0.35% (equivalent to approximately 10-microM dissolved oxygen). O2- production by the cell-free O2- -forming system prepared… CONTINUE READING