Effects of oxygen on zonal marker expression in human articular chondrocytes.

@article{Schrobback2012EffectsOO,
  title={Effects of oxygen on zonal marker expression in human articular chondrocytes.},
  author={Karsten Schrobback and Jos Malda and Ross Crawford and Zee Upton and David I. Leavesley and Travis Jacob Klein},
  journal={Tissue engineering. Part A},
  year={2012},
  volume={18 9-10},
  pages={920-33}
}
Articular cartilage is organized in depth zones with phenotypically distinct subpopulations of chondrocytes that are exposed to different oxygen tensions. Despite growing evidence of the critical role for oxygen in chondrogenesis, little is known about its effect on chondrocytes from different zones. This study evaluates zonal marker expression of human articular chondrocytes from different zones under various oxygen tensions. Chondrocytes isolated from full-thickness, superficial, and middle… CONTINUE READING
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Localization of the potential zonal marker clusterin in native cartilage and in tissue-engineered constructs

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