Effects of oxyfedrine on isolated portal vein and other smooth muscles.

@article{Mackenzie1973EffectsOO,
  title={Effects of oxyfedrine on isolated portal vein and other smooth muscles.},
  author={J E Mackenzie and James Roy Parratt},
  journal={British journal of pharmacology},
  year={1973},
  volume={47 4},
  pages={827-37}
}
1. Oxyfedrine (0.01-1.0 mug/ml), inhibited spontaneous myogenic activity in rat isolated portal vein and carbachol-induced contractions of rat isolated uterus, and relaxed the rabbit duodenum and the guinea-pig tracheal chain preparation. These actions were prevented by the beta-adrenoceptor blocking drug alprenolol. Oxyfedrine was a relatively weak beta-adrenoceptor stimulant (10-100 times less active than isoprenaline) but its actions were more prolonged.2. In the same concentrations… CONTINUE READING