Effects of overexpression of basic helix-loop-helix transcription factor Dec1 on osteogenic and adipogenic differentiation of mesenchymal stem cells.

@article{Iwata2006EffectsOO,
  title={Effects of overexpression of basic helix-loop-helix transcription factor Dec1 on osteogenic and adipogenic differentiation of mesenchymal stem cells.},
  author={Tomoyuki Iwata and Takeshi Kawamoto and Eri Sasabe and Kazuko Miyazaki and Katsumi Fujimoto and Mitsuhide Noshiro and Hidemi Kurihara and Yukio Kato},
  journal={European journal of cell biology},
  year={2006},
  volume={85 5},
  pages={423-31}
}
We recently reported that forced expression of basic helix-loop-helix transcription factor Dec1 accelerated chondrogenic differentiation of mesenchymal stem cells (MSC) in pellet cultures (Shen, M., Yoshida, E., Yan, W., Kawamoto, T., Suardita, K., Koyano, Y., Fujimoto, K., Noshiro, M., Kato, Y., 2002. Basic helix-loop-helix protein DEC1 promotes chondrocyte differentiation at the early and terminal stages. J. Biol. Chem. 277, 50112-50120). Since MSC have multilineage differentiation potential… CONTINUE READING

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