Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column.

Abstract

The effects of organic modifier and temperature on the enantioseparation of 10 triazoles and eight imidazoles, using supercritical fluid chromatography with the Chiralpak AD column, have been investigated in this work. For this purpose four different organic modifiers (methanol, ethanol, 2-propanol and acetonitrile) were evaluated. Only in the case of two… (More)
DOI: 10.1002/bmc.3013

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Cite this paper

@article{Toribio2014EffectsOO, title={Effects of organic modifier and temperature on the enantiomeric separation of several azole drugs using supercritical fluid chromatography and the Chiralpak AD column.}, author={Laura Toribio and Jos{\'e} Lu{\'i}s Bernal and M A T Mart{\'i}n and Ma Jes{\'u}s del Nozal}, journal={Biomedical chromatography : BMC}, year={2014}, volume={28 1}, pages={152-8} }