Effects of orexin A on thyrotropin-releasing hormone and thyrotropin secretion in rats.

@article{Mitsuma1999EffectsOO,
  title={Effects of orexin A on thyrotropin-releasing hormone and thyrotropin secretion in rats.},
  author={Terunori Mitsuma and Yoshifumi Hirooka and Yasumichi Mori and Makoto Kayama and Kyoichi Adachi and N Rhue and Jian Ma Quan Zhang Duanning Zhou Zhi Ping and Tsuyoshi Nogimori},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={1999},
  volume={31 11},
  pages={606-9}
}
Effects of orexin A on secretion of thyrotropin-releasing hormone (TRH) and thyrotropin (TSH) in rats were studied. Orexin A (50 microg/kg) was injected iv, and the rats were serially decapitated. The effects of orexin A on TRH release from the rat hypothalamus in vitro and on TSH release from the anterior pituitary in vitro were also investigated. TRH and thyroid hormone were measured by individual radioimmunoassays. TSH was determined by the enzyme-immunoassay method. The hypothalamic TRH… CONTINUE READING

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