Effects of oral treatments on clinical outcomes in pulmonary arterial hypertension: A systematic review and meta-analysis.

@article{Zhang2015EffectsOO,
  title={Effects of oral treatments on clinical outcomes in pulmonary arterial hypertension: A systematic review and meta-analysis.},
  author={Hong-Da Zhang and Ruiyan Zhang and Xin Jiang and Kai Sun and Dan-Chen Wu and Zhi-Cheng Jing},
  journal={American heart journal},
  year={2015},
  volume={170 1},
  pages={96-103, 103.e1-14}
}
BACKGROUND Many targeted therapies have been approved for pulmonary arterial hypertension (PAH), most of which are in oral forms. However, the effects of these drugs on lifesaving are unclear. Our objective was to evaluate the effects of oral treatments on clinical outcomes especially all-cause mortality in patients with PAH. METHODS MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched for relevant articles up to April 2014. Randomized, double-blind, parallel… CONTINUE READING
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