Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients.

@article{YoshimotoFuruie1999EffectsOO,
  title={Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients.},
  author={K Yoshimoto-Furuie and Keiichi Yoshimoto and Toshihiko Tanaka and Shigeki Saima and Yuichi Kikuchi and Jennifer Shay and David F. Horrobin and Hirotoshi Echizen},
  journal={Nephron},
  year={1999},
  volume={81 2},
  pages={151-9}
}
Abnormalities in plasma composition of essential fatty acids (EFAs) may be associated with the etiology of pruritus and other skin problems in patients undergoing hemodialysis. To study whether an oral supplementation with omega-6 (n-6) EFAs would restore deranged plasma EFAs and ameliorate skin symptoms, 9 and 7 dialysis patients were randomly assigned to receive either gamma-linolenic acid (GLA)-rich evening primrose oil (EPO) or linoleic acid (LA) (2 g/day each) for 6 weeks. Plasma… CONTINUE READING

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