Effects of opioid subtypes on detrusor overactivity in rats with cerebral infarction.

@article{Nagasaka2007EffectsOO,
  title={Effects of opioid subtypes on detrusor overactivity in rats with cerebral infarction.},
  author={Yasuhiro Nagasaka and Osamu Yokoyama and Kazuto Komatsu and Yoshiyuki Ishiura and Yasuo Nakamura and Mikio Namiki},
  journal={International journal of urology : official journal of the Japanese Urological Association},
  year={2007},
  volume={14 3},
  pages={
          226-31; discussion 232
        }
}
AIM In order to determine the influence of different opioid receptor subtypes on detrusor overactivity after left middle cerebral artery (MCA) occlusion, cystometric recordings were obtained in conscious rats. METHODS Female Sprague-Dawley rats were used in this study. Control cystometrography was followed by left MCA occlusion. The sham-operated (SO) rats underwent the same procedures except for MCA occlusion. [D-Ala(2), Phe(4), Gly(5)]-enkephalin (DAGO; mu-opioid agonist), [D-Pen(2,5… CONTINUE READING