Effects of oncotic agents as constituents of perfluorocarbon emulsions on the isolated heart

Abstract

The material currently used as an oncotic agent in emulsions of perfluoro-compounds (PFC) is frequently a hydroxyethylated starch (HES) [3-5], which has a volemitic effect, and is as effective as the usual materials based on dextran and blood albumin. The oncotic agents used in PFC emulsions intended for the perfusion of organs must satisfy certain requirements, viz., they must be nontoxic, compatible with the disperse phase of the emulsion, able to maintain the colloidal osmotic pressure at levels similar to that of the plasma proteins, and be of low viscosity.

DOI: 10.1007/BF00758316

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Cite this paper

@article{Vorobev2004EffectsOO, title={Effects of oncotic agents as constituents of perfluorocarbon emulsions on the isolated heart}, author={S. I. Vorob'ev and Bakhtior Islamov and E. I. Maevskii and S. M. Yarovaya and L. P. Grineva and G. S. Alekseeva and T. N. Telkova and O. Yu. Popova and V. A. Dombrovskii}, journal={Pharmaceutical Chemistry Journal}, year={2004}, volume={23}, pages={51-54} }