Effects of olanzapine on serum protein phosphorylation patterns in patients with schizophrenia.

@article{Jaros2015EffectsOO,
  title={Effects of olanzapine on serum protein phosphorylation patterns in patients with schizophrenia.},
  author={Julian A. J. Jaros and Hassan Rahmoune and Hendrik Wesseling and F. Markus Leweke and Sureyya Ozcan and Paul c. Guest and Sabine Bahn},
  journal={Proteomics. Clinical applications},
  year={2015},
  volume={9 9-10},
  pages={907-16}
}
PURPOSE Previous studies have shown that blood serum phosphoproteins are altered in schizophrenia patients in comparison to controls. However, it is not known whether phosphoproteins are also changed in response to treatment with antipsychotics. EXPERIMENTAL DESIGN Blood samples were taken from patients (n = 23) at baseline and after 6 weeks of olanzapine treatment. Immobilized metal ion affinity chromatography (IMAC) was used for enrichment of serum phosphoproteins and these were analyzed by… CONTINUE READING
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