Effects of oestrogen, administered early or late in the oestrous cycle, upon the survival and regression of the corpus luteum of the guinea-pig.

  title={Effects of oestrogen, administered early or late in the oestrous cycle, upon the survival and regression of the corpus luteum of the guinea-pig.},
  author={Doreen V. Illingworth and John S. Perry},
  journal={Journal of reproduction and fertility},
  volume={33 3},
In a study of the effects of estrogen administration (usually subcutaneous implantation between the shoulder blades) upon the guinea pig corpus luteum (CL) diethyl stilbestrol estradiol estradiol propionate and estradiol cypionate were administered in various experiments. Estrogen (50 mcg-75 mg) administered before Cycle Day 5 caused premature regression of the CL. After hysterectomy or hemihysterectomy no luteolytic effect occurred in the ovary on the side of the horn which had been removed… 

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Luteolytic effect of oestrogen on the corpora lutea of the cyclic guinea-pig.

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Reversal by gonadotrophins of the luteolytic effect of oestrogen in the cyclic guinea-pig.

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Effect of hysterectomy at different stages in the life cycle of the corpus luteum in the guinea-pig.

  • I. W. Rowlands
  • Medicine, Biology
    Journal of reproduction and fertility
  • 1961
The corpora lutea that formed post-operatively responded in the same way as those in animals operated on the 5th or 10th days of the luteal phase, and the nature of the stimulus of hysterectomy on the corpus luteum of the guinea-pig is discussed briefly.

Corpus luteum function in the guinea-pig; arterial and luteal progesterone levels, and the effects of hysterectomy and hypophysectomy.

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The effect of hypophysial stalk-section on the corpus luteum of the guinea-pig.

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Luteolytic Effect of Prostaglandin in the Guinea-pig

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Gonadal Hormones and the Regression of the Corpora Lutea in the Guinea-pig

The results of the following experiments involving the administration of oestrogen or progesterone indicate that the inhibitory effect of gonadal hormones on luteal function is exerted through the uterus and lends further support to the view that the uterus exercises a controlling influence on lutenal function in the guinea-pig.

Changes in the metabolic clearance rate of progesterone in the guinea-pig.

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