Effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward.

@article{Colle1988EffectsON,
  title={Effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward.},
  author={Lois M. Colle and R A Wise},
  journal={Brain research},
  year={1988},
  volume={459 2},
  pages={361-8}
}
The effects of amphetamine were examined in a brain stimulation reward paradigm in which response rate was measured across a range of stimulation frequencies. Both low (0.0625 and 0.125 mg/kg) and high (1.0, 2.0 and 4.0 mg/kg) doses of systemic amphetamine decreased the stimulation frequency needed to sustain low rates of responding; high doses decreased the maximal response rates that were sustained by the highest stimulation frequencies. Ipsilateral microinjections (2.5, 5.0 and 10.0… CONTINUE READING