Effects of novel human cathepsin S inhibitors on cell migration in human cancer cells.

@article{Tsai2014EffectsON,
  title={Effects of novel human cathepsin S inhibitors on cell migration in human cancer cells.},
  author={Ju-Ying Tsai and Mon-Juan Lee and Margaret Dah-Tsyr Chang and Hsin-Chieh Wang and Chun-Cheng Lin and Haimei Huang},
  journal={Journal of enzyme inhibition and medicinal chemistry},
  year={2014},
  volume={29 4},
  pages={538-46}
}
Elevated cathepsin S (Cat S) level is correlated with higher migration ability in tumor cells. This study investigates the inhibitory effect of novel synthetic α-ketoamide compounds on cathepsin activity and cancer cell migration. The effect of several α-ketoamide compounds on the activity of recombinant cathepsins (Cat S, Cat L and Cat K) was examined. Two… CONTINUE READING