Effects of normalization of plasma testosterone levels in hypogonadal men on plasma levels and urinary excretion of asymmetric dimethylarginine (ADMA).

@article{Leifke2008EffectsON,
  title={Effects of normalization of plasma testosterone levels in hypogonadal men on plasma levels and urinary excretion of asymmetric dimethylarginine (ADMA).},
  author={E. Leifke and M. Kinzel and D. Tsikas and L. Gooren and J. Fr{\"o}lich and G. Brabant},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2008},
  volume={40 1},
  pages={
          56-9
        }
}
  • E. Leifke, M. Kinzel, +3 authors G. Brabant
  • Published 2008
  • Medicine
  • Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Elevated plasma levels of asymmetric dimethylarginine (ADMA) inhibit nitric oxide formation and exert a proatherogenic action. Low testosterone (T) levels are associated with increased cardiovascular risks. This study analyzed the effects of normalization of plasma T levels on plasma levels and urinary excretion of ADMA in hypgonadal men (n=10) receiving transdermal T administration. Plasma T levels, starting from clearly hypogonadal T plasma concentrations with a mean level of 4.0+/-2.72 nmol… Expand
Determination of asymmetric dimethylarginine in biological fluids: a paradigm for a successful analytical story
  • D. Tsikas
  • Chemistry, Medicine
  • Current opinion in clinical nutrition and metabolic care
  • 2008
Connecting the Lines between Hypogonadism and Atherosclerosis