Effects of norepinephrine on the proximal tubular cells in perfused bullfrog kidney.
@article{Kubota1989EffectsON, title={Effects of norepinephrine on the proximal tubular cells in perfused bullfrog kidney.}, author={T. Kubota and N. Hagiwara and M. Kubokawa and M. Fujimoto}, journal={Bulletin of the Osaka Medical College}, year={1989}, volume={35 1-2}, pages={ 11-9 } }
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To study effects of norepinephrine (NE) on sodium and hydrogen ion transport, we used H(+)-, Ca2(+)-, or Na(+)-selective microelectrode and split-oil droplet techniques in doubly-perfused bullfrog proximal tubules. Peritubular membrane potential difference (EM), intracellular activities of Na+ ((Na)i) and Ca2+ ((Ca)i), and pH of the cytosol (pHi) and the lumen (pHTF) were monitored continuously during peritubular administration of NE (10(-6)-10(-7) M), phenylephrine (PHE, 10(-7) M… CONTINUE READING
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