Effects of noradrenaline and somatostatin on basal and stimulated mucosal ion transport in the guinea-pig small intestine

@article{Keast1986EffectsON,
  title={Effects of noradrenaline and somatostatin on basal and stimulated mucosal ion transport in the guinea-pig small intestine},
  author={Janet R. Keast and John Barton Furness and Marcello Costa},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1986},
  volume={333},
  pages={393-399}
}
Noradrenaline (NA) and somatostatin (SOM) stimulate intestinal water and ion absorption and are found in mucosal nerve fibres and nerve terminals in submucous ganglia of the guinea-pig small intestine. As the main projection of submucous neurons is to the mucosa, NA and SOM might alter mucosal transport either by a direct effect on the epithelium or indirectly, by affecting submucous neurons. In this study these two possible sites of action of NA and SOM have been investigated in mucosa… CONTINUE READING

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