Effects of nonocclusive mesenteric hypertension on intestinal function: implications for gastroschisis-related intestinal dysfunction

@article{Shah2012EffectsON,
  title={Effects of nonocclusive mesenteric hypertension on intestinal function: implications for gastroschisis-related intestinal dysfunction},
  author={Shinil K Shah and Kevin R. Aroom and Peter A. Walker and Hasen Xue and Fernando Jim{\'e}nez and Brijesh S. Gill and Charles S. Cox and Stacey D. Moore-Olufemi},
  journal={Pediatric Research},
  year={2012},
  volume={71},
  pages={668-674}
}
Introduction:Infants with gastroschisis (GS) have significant morbidity from dysmotility, feeding intolerance, and are at increased risk of developing intestinal failure. Although the molecular mechanisms regulating GS-related intestinal dysfunction (GRID) are largely unknown, we hypothesized that mechanical constriction (nonocclusive mesenteric hypertension (NMH)) from the abdominal wall defect acts as a stimulus for GRID. The purpose of this study was to determine the effect of NMH on… CONTINUE READING

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