Effects of nonlinear propagation, cavitation, and boiling in lesion formation by high intensity focused ultrasound in a gel phantom.

@article{Khokhlova2006EffectsON,
  title={Effects of nonlinear propagation, cavitation, and boiling in lesion formation by high intensity focused ultrasound in a gel phantom.},
  author={Vera A. Khokhlova and Michael R. Bailey and Justin A. Reed and Bryan W. Cunitz and Peter J. Kaczkowski and Lawrence A. Crum},
  journal={The Journal of the Acoustical Society of America},
  year={2006},
  volume={119 3},
  pages={
          1834-48
        }
}
The importance of nonlinear acoustic wave propagation and ultrasound-induced cavitation in the acceleration of thermal lesion production by high intensity focused ultrasound was investigated experimentally and theoretically in a transparent protein-containing gel. A numerical model that accounted for nonlinear acoustic propagation was used to simulate experimental conditions. Various exposure regimes with equal total ultrasound energy but variable peak acoustic pressure were studied for single… 

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