Effects of noise on the off rate of Ca(2+) binding proteins in a coupled biochemical cell system.

@article{Zhang2001EffectsON,
  title={Effects of noise on the off rate of Ca(2+) binding proteins in a coupled biochemical cell system.},
  author={Jie Zhang and Feng Qi and Houwen Xin},
  journal={Biophysical chemistry},
  year={2001},
  volume={94 3},
  pages={201-7}
}
We investigated numerically the kinetic properties of calcium binding proteins by using a three-calcium store model and discussed the response of a two-way coupled biochemical cell system, whose subsystems were coupled via diffusion-like cytosolic calcium transfer through gap junctions, to the external stimulation. When we used noise to modulate the off rate of the Ca(2+) binding proteins in simulation, an SR-like phenomenon of synchronous oscillations is observed. In addition, the interaction… CONTINUE READING