Effects of nocodazole and brefeldin A on microtubule cytoskeleton and membrane organization in the homobasidiomyceteSchizophyllum commune

@article{Rupe2005EffectsON,
  title={Effects of nocodazole and brefeldin A on microtubule cytoskeleton and membrane organization in the homobasidiomyceteSchizophyllum commune},
  author={Ivan Rupe{\vs} and W. -Z. Mao and Helena {\AA}str{\"o}m and Marjatta Raudaskoski},
  journal={Protoplasma},
  year={2005},
  volume={185},
  pages={212-221}
}
SummaryThe effects of nocodazole and brefeldin A (BFA) on the growth of dikaryotic hyphae inSchizophyllum commune corresponded with the development of abnormal structures in the apical region of treated hyphae. Microtubules (MTs) were totally depolymerized after 1 h nocodazole treatment, which correlated with strong branch formation in the apical cells. One reason for branching could be the shift in the position of apical vesicles from the center to the side of the tip, observed in some… 
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The observations show that the Mt cytoskeleton is involved in maintaining the polarity and growth pattern of apical cells, and mitosis is blocked by low concentrations of Nz without significant depolymerization of Mts, and the centrosome cycle is independent of the nuclear cycle.
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TLDR
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TLDR
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TLDR
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