Effects of nocloprost on gastric functions in man.

  title={Effects of nocloprost on gastric functions in man.},
  author={Stanisław Jan Konturek and Nina Kwiecień and Wojciech Obtulowicz and J Maczka and Z Hebzda and Jan Oleksy},
  journal={Scandinavian journal of gastroenterology},
  volume={26 11},
Previous studies in animals and humans demonstrated that nocloprost, a stable prostaglandin E2 analogue, shows very high gastroprotective potency, relatively weak gastric inhibitory activity, and low systemic bioavailability after oral administration. In this study the effects of nocloprost on gastric acid secretion and intraluminal pH and on gastric… CONTINUE READING