Effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward

  title={Effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward},
  author={N. Benturquia and T. L. Marec and J. Scherrmann and F. Noble},
Recently we have shown that nitrous oxide (N2O) was able to block the expression of morphine-induced conditioned place preference (CPP) in mice. Because dopamine (DA) has also been associated with the positive place conditioning we hypothesize that exposure to N2O would be significantly associated with a modification of extracellular level of DA. Unbiased place conditioning method was used for mice and rats. Levels of DA, in the nucleus accumbens (Nac), in awake and freely moving rats during… Expand
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