Effects of nitric oxide synthase inhibitors and a substrate, L-arginine, on the cardiac function of juvenile salmonid fish.

@article{Eddy2003EffectsON,
  title={Effects of nitric oxide synthase inhibitors and a substrate, L-arginine, on the cardiac function of juvenile salmonid fish.},
  author={Francesca Eddy and Phillip A. Tibbs},
  journal={Comparative biochemistry and physiology. Toxicology & pharmacology : CBP},
  year={2003},
  volume={135 2},
  pages={
          137-44
        }
}
Control of cardiac function was investigated juvenile brown trout (Salmo trutta L.) and rainbow trout (Oncorhynchus mykiss Walbaum) using inhibitors of nitric oxide synthase (NOS), (L-NAME, NG-nitro-L-arginine and L-NMMA, NG-monomethyl-L-arginine) and a substrate of NOS (L-arginine). Salmonid alevins are excellent models for such studies since they are transparent, the beating heart is easily observed, diffusing distances are small, and they respond within a few seconds to exogenously… CONTINUE READING
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