Effects of nitric oxide on red blood cell deformability.

@article{BorKucukatay2003EffectsON,
  title={Effects of nitric oxide on red blood cell deformability.},
  author={Melek Bor-Kucukatay and Rosalinda B. Wenby and Herbert J. Meiselman and Oguz K. Baskurt},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2003},
  volume={284 5},
  pages={
          H1577-84
        }
}
In addition to its known action on vascular smooth muscle, nitric oxide (NO) has been suggested to have cardiovascular effects via regulation of red blood cell (RBC) deformability. The present study was designed to further explore this possibility. Human RBCs in autologous plasma were incubated for 1 h with NO synthase (NOS) inhibitors [N(omega)-nitro-l-arginine methyl ester (l-NAME) and S-methylisothiourea], NO donors [sodium nitroprusside (SNP) and diethylenetriamine (DETA)-NONOate], an NO… 

Figures from this paper

Modulation of density-fractionated RBC deformability by nitric oxide.

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RBC-NOS-Dependent S-Nitrosylation of Cytoskeletal Proteins Improves RBC Deformability

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