Effects of nitric oxide on blood flow and mucociliary activity in the human nose.

@article{Runer1998EffectsON,
  title={Effects of nitric oxide on blood flow and mucociliary activity in the human nose.},
  author={T Runer and Sven Lindberg},
  journal={The Annals of otology, rhinology, and laryngology},
  year={1998},
  volume={107 1},
  pages={40-6}
}
In an animal model, nitric oxide (NO) has been shown to increase mucociliary activity in vivo and ciliary beat frequency in vitro. The aim of the present study was to investigate the effects of NO on blood flow and mucociliary activity in the human nose. The concentration of NO in nasal air was measured with a chemiluminescence technique after nebulizing the NO donor sodium nitroprusside (SNP) at a dose of 3.0 mg into the nose in six volunteers, and was found to increase by 50.1% +/- 10.0… CONTINUE READING

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