Corpus ID: 22256720

Effects of nitric oxide on antral motility and gastric emptying in humans.

@article{Konturek1995EffectsON,
  title={Effects of nitric oxide on antral motility and gastric emptying in humans.},
  author={J. Konturek and P. Thor and W. Domschke},
  journal={European journal of gastroenterology \& hepatology},
  year={1995},
  volume={7 2},
  pages={
          97-102
        }
}
OBJECTIVE It has been suggested that nitric oxide is a nonadrenergic-noncholinergic (NANC) inhibitory neurotransmitter released by the nerves in the gastrointestinal tract. We studied the influence of nitric oxide on gastric emptying and antral motility using glyceryl trinitrate (GTN), a donor of nitric oxide and L-arginine as the substrate of nitric oxide synthase. DESIGN Six male volunteers (aged 21-24 years) participated in this placebo-controlled, double-blind study. METHODS We… Expand
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