Effects of nicorandil on cardiovascular events in patients with coronary artery disease in the Japanese Coronary Artery Disease (JCAD) study.

@article{Horinaka2010EffectsON,
  title={Effects of nicorandil on cardiovascular events in patients with coronary artery disease in the Japanese Coronary Artery Disease (JCAD) study.},
  author={Shigeo Horinaka and Akihisa Yabe and Hiroshi Yagi and Toshihiko Ishimitsu and Tsutomu Yamazaki and Shinya Suzuki and Takahide Kohro and Ryozo Nagai},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2010},
  volume={74 3},
  pages={503-9}
}
BACKGROUND Nicorandil has cardioprotective effects in the ischemic myocardium, mimicking ischemic preconditioning, and is thus expected to improve the prognosis of ischemic heart disease (IHD). As part of the Japanese Coronary Artery Disease (JCAD) Study, a multicenter collaborative prospective observational study of a large cohort of coronary artery disease patients, the effect of nicorandil on outcome was examined. METHODS AND RESULTS In total, 2,558 patients with nicorandil treatment and… CONTINUE READING

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