Effects of neuropeptides on neutrophil migration through noncellular and endothelial barriers.

BACKGROUND Neuropeptides and neutrophils are postulated to be important immune effector molecules and cells, respectively, in a variety of lung inflammatory conditions. METHODS We examined the effects of three lung neuropeptides, substance P, vasoactive intestinal peptide (VIP), and somatostatin and two relatively protease-resistant peptides, helodermin… CONTINUE READING