Effects of neonatal treatment with clomipramine on adult ethanol related behavior in the rat.

@article{Hilakivi1984EffectsON,
  title={Effects of neonatal treatment with clomipramine on adult ethanol related behavior in the rat.},
  author={Leena A. Hilakivi and John David Sinclair and I T Hilakivi},
  journal={Brain research},
  year={1984},
  volume={317 1},
  pages={129-32}
}
Male rat pups were deprived of active (REM) sleep by giving daily injections of clomipramine between 8 and 21 days after birth. At the age of 55 days their ambulation and defecation in the open-field were tested. Thereafter, beginning at the age of 66 days, the voluntary ethanol consumption of the rats was tested for 4 weeks. Compared to saline-treated rats, the CLM rats consumed more ethanol, tended to be more active in the open-field, and responded with a decrease in ambulation to an ethanol… CONTINUE READING

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