Effects of naturally acquired decompensated mitral valve regurgitation on the renin-angiotensin-aldosterone system and atrial natriuretic peptide concentration in dogs.

@article{Hggstrm1997EffectsON,
  title={Effects of naturally acquired decompensated mitral valve regurgitation on the renin-angiotensin-aldosterone system and atrial natriuretic peptide concentration in dogs.},
  author={Jens H{\"a}ggstr{\"o}m and K. S. A. Hansson and Clarence Kvart and B. E. Karlberg and Olli Jaakko Vuolteenaho and Kerstin Klingberg Olsson},
  journal={American journal of veterinary research},
  year={1997},
  volume={58 1},
  pages={
          77-82
        }
}
OBJECTIVE To investigate activity of the renin-angiotensin-aldosterone system and N-terminal pro-atrial natriuretic peptide (NT-proANP) during development of clinical signs of decompensated mitral valve regurgitation (MR). ANIMALS 11 Cavalier King Charles Spaniels with advanced MR attributable to chronic valvular disease. PROCEDURE Dogs were subjected to repeated examinations at 6-month intervals until signs of decompensation had developed (end point). Data acquired at end point were… CONTINUE READING

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