Effects of nateglinide and glibenclamide on postprandial lipid and glucose metabolism in type 2 diabetes

@article{Vakkilainen2002EffectsON,
  title={Effects of nateglinide and glibenclamide on postprandial lipid and glucose metabolism in type 2 diabetes},
  author={Juha Vakkilainen and Niina Mero and A. F. Schweizer and James E Foley and Marja-Riitta Taskinen},
  journal={Diabetes/metabolism research and reviews},
  year={2002},
  volume={18 6},
  pages={
          484-90
        }
}
BACKGROUND Postprandial hyperlipemia and small, dense LDL particles are features of dyslipidemia in type 2 diabetes. The purpose of this study was (1) to determine whether the oral insulinotropic drugs, nateglinide and glibenclamide, can overcome the defect of insulin action to suppress the hepatic VLDL release after a meal and decrease the postprandial lipemia and (2) to evaluate the acute effect of postprandial hypertriglyceridemia on LDL particle size in subjects with type 2 diabetes… CONTINUE READING
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