Effects of narrowband UV-B on pharmacodynamic markers of response to therapy: an immunohistochemical study over sequential samples.

@article{Carrascosa2007EffectsON,
  title={Effects of narrowband UV-B on pharmacodynamic markers of response to therapy: an immunohistochemical study over sequential samples.},
  author={Jos{\'e} Manuel Carrascosa and G. Pullas Tapia and Isabel Roca Bielsa and M C Fuente and Carlos Ferr{\'a}ndiz},
  journal={Journal of cutaneous pathology},
  year={2007},
  volume={34 10},
  pages={769-76}
}
BACKGROUND To evaluate the effects of narrow-band UV-B (NBUVB) on the immunohistochemical markers of cellular and cytokine activation as well as of abnormal epidermal differentiation and proliferation--pharmacodynamic markers of response to therapy (PMT)--in psoriatic lesions. METHODS Clinical assessments and immunohistological staining of formalin-fixed paraffin sections of biopsies from psoriatic skin were done at baseline and at the end of the treatment period. RESULTS Ten patients with… CONTINUE READING
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