Effects of nanomaterial physicochemical properties on in vivo toxicity.

  title={Effects of nanomaterial physicochemical properties on in vivo toxicity.},
  author={Kristin L Aillon and Yumei Xie and Nashwa El-gendy and Cory J Berkland and M Laird Forrest},
  journal={Advanced drug delivery reviews},
  volume={61 6},
It is well recognized that physical and chemical properties of materials can alter dramatically at nanoscopic scale, and the growing use of nanotechnologies requires careful assessment of unexpected toxicities and biological interactions. However, most in vivo toxicity concerns focus primarily on pulmonary, oral, and dermal exposures to ultrafine particles. As nanomaterials expand as therapeutics and as diagnostic tools, parenteral administration of engineered nanomaterials should also be… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 166 extracted citations


Publications referenced by this paper.
Showing 1-10 of 122 references

Poly(propyleneimine) dendrimers as pH-sensitive controlled-release systems. Chem.-Eur

  • G Pistolis, A Malliaris, D Tsiourvas, CM. Paleos
  • J 1999;5:1440–1444
  • 1999
Highly Influential
12 Excerpts

Toxicological effects of mult-wall carbon nanotubes in rats

  • A Liu, K Sun, J Yang, D. Zhao
  • J. Nanopart. Res 2008;10:1303–1307
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…