Effects of naltrexone on self-injury, stereotypy, and social behavior of adults with developmental disabilities

@article{Smith1995EffectsON,
  title={Effects of naltrexone on self-injury, stereotypy, and social behavior of adults with developmental disabilities},
  author={S. Smith and K. Gupta and S. H. Smith},
  journal={Journal of Developmental and Physical Disabilities},
  year={1995},
  volume={7},
  pages={137-146}
}
  • S. Smith, K. Gupta, S. H. Smith
  • Published 1995
  • Psychology
  • Journal of Developmental and Physical Disabilities
  • We examined the effects of long term administration of naltrexone on the severe self-injury, stereotypy, and social behavior of two women with developmental disabilities. A single-subject withdrawal design was used. Results indicated naltrexone eliminated self-injury and stereotypy, and increased smiling, eye-contact, and touch tolerance duration. Psychophysiological (finger temperature) data indicated that untreated self-injurious behavior induced vasodiolation, and that naltrexone induced a… CONTINUE READING
    18 Citations
    Self-injurious behavior and the efficacy of naltrexone treatment: a quantitative synthesis.
    • 131
    • PDF
    Using analog baselines to assess the effects of naltrexone on self-injurious behavior.
    • 36
    Proopiomelanocortin (POMC) disregulation and response to opiate blockers
    • 44
    Stereotypy II: a review of neurobiological interpretations and suggestions for an integration with behavioral methods.
    • 46
    Duration of opioid receptor blockade determines biotherapeutic response.
    • 28
    Stereotypic behavior in nonhuman primates as a model for the human condition.
    • C. Lutz
    • Medicine, Psychology
    • ILAR journal
    • 2014
    • 15
    • PDF

    References

    SHOWING 1-10 OF 11 REFERENCES
    B‐endorphin disregulation in autistic and self‐injurious behavior: A neurodevelopmental hypothesis
    • 106
    Pharmacotherapy in the developmental disabilites: New developments
    • 15
    Reduction of elevated CSF beta-endorphin by fenfluramine in infantile autism.
    • 39
    Endorphin activity in childhood psychosis. Spinal fluid levels in 24 cases.
    • 175
    The Opiate Hypothesis in Autism and Self-Injury
    • 81
    Influence of naloxone on brain and behavior of a self-injurious woman
    • 38