Effects of mutations in the X gene of hepatitis B virus on the virus replication.

Abstract

UNLABELLED Previously, we have found a new mutation at nt 1726-1730 that is associated with lower hepatitis B virus (HBV) DNA levels in the liver, and mutations at nt 1762/1764 that are correlated with higher HBV DNA levels. To confirm the effects of these mutations on the virus replication efficiency, substitutions nt 1726-1730 CTGAG and A1762T/G1764A in… (More)

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@article{Yu2012EffectsOM, title={Effects of mutations in the X gene of hepatitis B virus on the virus replication.}, author={Hui Yu and Rong Zhu and Ya-zhen Zhu and Qi Chen and Hong-guang Zhu}, journal={Acta virologica}, year={2012}, volume={56 2}, pages={101-10} }