Effects of mosapride on esophageal functions and gastroesophageal reflux.

@article{Koshino2010EffectsOM,
  title={Effects of mosapride on esophageal functions and gastroesophageal reflux.},
  author={Kenji Koshino and Kyoichi Adachi and Kenji Furuta and Shunji Ohara and Terumi Morita and Shuji Nakata and Takashi Tanimura and Masaharu Miki and Yoshiyuki Kinoshita},
  journal={Journal of gastroenterology and hepatology},
  year={2010},
  volume={25 6},
  pages={
          1066-71
        }
}
BACKGROUND AND AIM A substantial number of patients with gastroesophageal reflux disease show symptomatic resistance to high-dose proton pump inhibitors. In those cases, prokinetics are possible candidates for treatment. The aim of the present study was to determine whether mosapride, a prokinetic agent, stimulates esophageal functions, and prevents acidic and non-acidic gastroesophageal reflux. METHODS Normal volunteers (nine and 13 for two experiments, respectively) were enrolled. Salivary… CONTINUE READING

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