Effects of morphine and naloxone on play-rewarded spatial discrimination in juvenile rats.

@article{Normansell1990EffectsOM,
  title={Effects of morphine and naloxone on play-rewarded spatial discrimination in juvenile rats.},
  author={L Normansell and Jaak Panksepp},
  journal={Developmental psychobiology},
  year={1990},
  volume={23 1},
  pages={75-83}
}
Juvenile rats were trained on a spatial discrimination task (T-maze) rewarded by the opportunity to play with a conspecific. Neither morphine (MS; 1 mg/kg) nor naloxone (NX; 1 mg/kg) administration affected choice or running time during the acquisition of the task, even though in the goal box, MS-treated animals played more than and NX-treated animals less than vehicle-treated controls. Thus, brain opioid systems seem to influence the expression of play without affecting the apparent appetitive… CONTINUE READING

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