Effects of morphine and heroin on discrimination learning and consolidation in mice

  title={Effects of morphine and heroin on discrimination learning and consolidation in mice},
  author={Claudio Castellano},
Morphine and heroin were administered to mice learning to swim toward a light source (l procedure) or toward the dark (d procedure), in a Y water maze, under pre- and post-trial drug treatment conditions. In the pre-trial experiments a clear disrupting effect on performance with the two procedures followed administration of both drugs, but for the l procedure, performance never fell below the 50% level of correct choices. Analysis of the performance within each session demonstrated a disruption… CONTINUE READING

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