Effects of morin on snake venom phospholipase A2 (PLA2).

  title={Effects of morin on snake venom phospholipase A2 (PLA2).},
  author={Carolina Veras Iglesias and Ricardo Apar{\'i}cio and L{\'e}a Rodrigues-Simioni and Enilton Aparecido Camargo and Edson Antunes and S{\'e}rgio Marangoni and Daniela de Oliveira Toyama and Luis O S Beriam and H. Monteiro and Marcos Hikari Toyama},
  journal={Toxicon : official journal of the International Society on Toxinology},
  volume={46 7},
Flavonoids are potent anti-inflammatory compounds isolated from several plant extracts, and have been used experimentally against inflammatory processes. In this work, a PLA2 isolated from the Crotalus durissus cascavella venom and rat paw oedema were used as a model to study the effect of flavonoids on PLA2. We observed that a treatment of PLA2 with morin induces several modifications in the aromatic amino acids, with accompanying changes in its amino acid composition. In addition, results… CONTINUE READING


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