Effects of monoamine uptake inhibitors given early postnatally on monoamines in the brain stem, caudate/putamen and cortex, and on dopamine D1 and D2 receptors in the caudate/putamen

@article{Hilakivi1995EffectsOM,
  title={Effects of monoamine uptake inhibitors given early postnatally on monoamines in the brain stem, caudate/putamen and cortex, and on dopamine D1 and D2 receptors in the caudate/putamen},
  author={I T Hilakivi and Liisa Ahtee and Juha O. Rinne and Tomi Taira and L. M. J. Attila and P{\"a}ivi Marjam{\"a}ki},
  journal={Journal of Neural Transmission / General Section JNT},
  year={1995},
  volume={102},
  pages={139-148}
}
Rats were treated with desipramine 5mg/kg, nomifensine 10mg/kg, zimelidine 25 mg/kg or with 0.9% sodium chloride once a day during the second and third weeks after birth, and brain stem, caudate/putamen and cortical monoamines, and caudate/putamen dopamine D1 (3[H]SCH 23390) and D2 (3[H]spiroperidol) receptor binding were measured when rats were at two months of age. In the brain stem, the concentration of 3-methoxy-4-hydroxy-phenyl glycol was increased in nomifensine rats and the ratio of 5… CONTINUE READING