Effects of mineralocorticoid receptor antagonist spironolactone on atrial conduction and remodeling in patients with heart failure.

@article{Kimura2011EffectsOM,
  title={Effects of mineralocorticoid receptor antagonist spironolactone on atrial conduction and remodeling in patients with heart failure.},
  author={Masayasu Kimura and Hiroshi Ogawa and Takatoshi Wakeyama and Akira Takaki and Takahiro Iwami and Yasuyuki Hadano and Mamoru Mochizuki and Atsushi Hiratsuka and Akihiko Shimizu and Masunori Matsuzaki},
  journal={Journal of cardiology},
  year={2011},
  volume={57 2},
  pages={208-14}
}
BACKGROUND Spironolactone was shown to reduce mortality in patients with heart failure (HF). However, the effect of spironolactone on the incidence of atrial fibrillation remains unknown. Therefore, we examined the effects of spironolactone on atrial conduction and remodeling in patients with HF. METHODS AND RESULTS A total of 21 patients with HF were divided into either spironolactone group (n=11) or control group (n=10). The patients were followed up for 12 months. Blood examination… CONTINUE READING

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