Effects of milk fermented byLactobacillusgasseri SBT2055 on adipocyte size in rats
@article{Sato2008EffectsOM,
title={Effects of milk fermented byLactobacillusgasseri SBT2055 on adipocyte size in rats},
author={Masao Sato and Kazunori Uzu and Takeshi Yoshida and Essam M. Hamad and Hiroshi Kawakami and Hiroaki Matsuyama and Ibrahim A Abd El-Gawad and Katsumi Imaizumi},
journal={British Journal of Nutrition},
year={2008},
volume={99},
pages={1013 - 1017}
}Despite adequate scientific evidence of the potential benefits of probiotics to human health or disease prevention, their contribution to the growth of adipose tissue remains to be established. Four-week-old male Sprague-Dawley rats were fed a diet containing skim milk (control diet) or skim milk fermented by Lactobacillus gasseri SBT2055 (LGSP diet) for 4 weeks. Their body weight gain, adipose tissue weight, adipocyte size distribution profile, blood and hepatic lipids, and serum leptin…
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Milk fermented by Lactobacillus gasseri SBT2055 influences adipocyte size via inhibition of dietary fat absorption in Zucker rats.
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It is demonstrated previously that a diet containing skimmed milk fermented by Lactobacillus gasseri SBT2055 reduces adipocyte size in Sprague-Dawley rats, and results indicate that fermented milk regulates adipose tissue growth through inhibition at the stage of dietary fat absorption in lean Zucker rats.
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LG2055 significantly prevented body weight gain, fat accumulation and pro-inflammatory gene expression in the adipose tissue, and it is suggested that improvement in the inflammatory state of the adiposity might be a possible mechanism underlying the anti-obesity effect of LG2055.
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The results demonstrate that, in addition to the inhibition of dietary TAG absorption reported previously, the intake of probiotic LG2055 enhanced energy expenditure via carbohydrate oxidation, improved glucose tolerance and attenuated inflammation, suggesting multiple additive and/or synergistic actions underlying the anti-obesity effects exerted byLG2055.
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