Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro.

@article{Li2004EffectsOM,
  title={Effects of mifepristone on proliferation of human gastric adenocarcinoma cell line SGC-7901 in vitro.},
  author={D. Li and Z. Wang and J. Bai and J. Zhao and Y. Wang and K. Hu and Yong-hong Du},
  journal={World journal of gastroenterology},
  year={2004},
  volume={10 18},
  pages={
          2628-31
        }
}
  • D. Li, Z. Wang, +4 authors Yong-hong Du
  • Published 2004
  • Biology, Medicine
  • World journal of gastroenterology
  • AIM To explore the effects of mifepristone, a progesterone receptor (PR) antagonist, on the proliferation of human gastric adenocarcinoma cell line SGC-7 901 in vitro and the possible mechanisms involved. METHODS In situ hybridization was used to detect the expression of PR mRNA in SGC-7901 cells. After treatment with various concentrations of mifepristone (2.5, 5, 10, 20 micromol/L) at various time intervals, the ultrastructural changes, cell proliferation, cell-cycle phase distribution, and… CONTINUE READING

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