Effects of microgravity on osteoclast bone resorption and osteoblast cytoskeletal organization and adhesion.

@article{Nabavi2011EffectsOM,
  title={Effects of microgravity on osteoclast bone resorption and osteoblast cytoskeletal organization and adhesion.},
  author={Noushin Nabavi and Arian Khandani and Anne Camirand and Rene E Harrison},
  journal={Bone},
  year={2011},
  volume={49 5},
  pages={
          965-74
        }
}
Exposure to microgravity has been associated with several physiological changes in astronauts, including an osteoporosis-like loss in bone mass. Despite many in vivo and in vitro studies in both microgravity and simulated microgravity conditions, the mechanism for bone loss is still not clear. The lack of weight-bearing forces makes microgravity an ideal physical stimulus to assess bone cell responses. In this work, we conduct a unique investigation of the effects of microgravity on bone… CONTINUE READING
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