Effects of methylprednisolone on hydrogen ion absorption in the canine stomach.

  • R S Chung, M Field, William Silen
  • Published 1978 in The Journal of clinical investigation


The effect of methylprednisolone (2 mg/kg per day given parenterally for 3 doses, 2 wk or 12 wk) on the permeability of mammalian gastric mucosa to hydrogen ion (H(+)) was examined with denervated fundic pouches in dogs with antrectomies. Transmucosal electric potential difference (PD) and net fluxes of H(+) and Na(+) were determined for luminal [H(+)] from… (More)


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