Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies.

@article{Swartz1992EffectsOM,
  title={Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies.},
  author={William J. Swartz and M Corkern},
  journal={Reproductive toxicology},
  year={1992},
  volume={6 5},
  pages={431-7}
}
This study was designed to assess whether exposure to the estrogenic pesticide methoxychlor (MXC) during pregnancy would affect reproductive parameters not only in female offspring exposed prenatally, but also in those of a subsequent litter. Mice were exposed via oral gavage to 7.5, 5.0, or 2.5 mg technical grade MXC (50%) or 0.025 mg estradiol-17 beta (E-17 beta) from days 6 to 15 of pregnancy. Following delivery, female offspring (F1a) were cross-fostered and sacrificed at 8 weeks of age… CONTINUE READING

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