Effects of methotrexate on rabbit testes. Part 2: Hormonal changes.

Abstract

Thirty mature and peripubertal male rabbits were examined for endocrine function and tissue methotrexate (MTX) concentration after single (57.5 mg/kgBW, group 1) and repeated (6 mg/kgBW, once a week for 14 weeks, group 2) MTX doses. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and androstenedione plasma levels were measured by… (More)

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Cite this paper

@article{Khler1986EffectsOM, title={Effects of methotrexate on rabbit testes. Part 2: Hormonal changes.}, author={Margrit K{\"{o}hler and Udo E Heinrich and Rolf Ludwig and Ruediger Waldherr and Werner E. Brandeis}, journal={Pediatric hematology and oncology}, year={1986}, volume={3 4}, pages={335-41} }